* Therapeutic indications: | ||
# Treatment of depressive states of varying aetiology and symptomatology, e.g. | ||
– endogenous, reactive, neurotic, organic, masked, and involutional forms of depression, | ||
– depression associated with schizophrenia and personality disorders, | ||
– depressive syndromes due to presenility or senility, to chronic painful conditions, and | ||
& chronic somatic diseases. | ||
– depressive mood disorders of a reactive, neurotic, or psychopathic nature. | ||
# Obsessive-compulsive syndromes. | ||
# Phobias and panic attacks. | ||
# Cataplexy accompanying narcolepsy. | ||
# Chronic painful conditions. | ||
# Nocturnal enuresis (only in patients over the age of 5 and if organic causes have been excluded). | ||
* Posology and method of administration: | ||
– The dosage and method of administration should be adapted to the individual patient’s condition. | ||
& The aim is to achieve an optimum effect while keeping the doses as low as possible and increasing them | ||
& cautiously, particularly in elderly patients or adolescents, who generally show a stronger response to | ||
& Anafronil than patients of intermediate age groups. | ||
– Depression, obsessive-compulsive syndromes, and phobias: Start treatment with 1 coated tablet of 25 mg | ||
& 2-3 times daily or 1 sustained-release tablet of 75 mg once daily (preferably in the evening). Raise the daily | ||
& dosage stepwise, e.g. 25 mg every few days, (depending on how the medication is tolerated) to 4-6 tablets | ||
& of 25 mg or 2 sustained-release tablets of 75 mg during the first week of treatment. In severe cases this dosage | ||
& can be increased up to a maximum of 250 mg daily. Once there is a distinct improvement, adjust the daily dosage | ||
& to a maintenance level of about 2-4 coated tablets of 25 mg or 1 modified-release tablet of 75 mg. | ||
– Panic attacks, agoraphobia: Start with 1 tablet of 10 mg daily, possibly in combination with a benzodiazepine. | ||
& Depending on how the medication, while gradually withdrawing the benzodiazepine. The daily dosage required | ||
& varies greatly from patient to patient and lies between 25 and 100 mg. If necessary it can be increased to 150mg. | ||
& It is advisable for treatment not to be dicontinued for at least 6 months and for the maintenance dose to be | ||
& reduced slowly during this time. | ||
– Cataplexy accompanying narcolepsy: Daily dose of 25-75 mg. | ||
– Chronic painful conditions: The dosage must be individualised (10-150 mg daily), while taking account of | ||
& concomitant analgesic medication (and of the possibility of reducing use of analgesics). | ||
– Elderly patients: Start treatment with 1 tablet of 10 mg daily. Gradually raise the dosage to an optimum level of | ||
& 30-50 mg daily, which should be reached after about 10 days and then maintained until the end of treatment. | ||
– Nocturnal enuresis: Initial
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ANAFRONIL 25 MG 30 TAB
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45.00 EGP
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