* Therapeutic indications: |
& Aricept tablets are indicated for the symptomatic treatment of mild to moderately severe Alzheimer’s dementia. |
* Posology and method of administration: |
# Adults / Elderly: |
– Treatment is initiated at 5 mg / day (once-a-day dosing). ARICEPT tablets should be taken orally, in the evening, just prior to |
& retiring. The 5 mg / day dose should be maintained for at least one month in order to allow the earliest clinical responses to |
& treatment to be assessed and to allow steady-state concentrations of donepezil hydrochloride to be achieved. Following |
& a one-month clinical assessment of treatment at 5 mg / day, the dose of ARICEPT can be increased to 10 mg / day (once-a-day |
& dosing). The maximum recommended daily dose is 10 mg. Doses greater than 10 mg / day have not been studied in clinical trials. |
& Upon discontinuation of treatment, a gradual abatement of the beneficial effects of ARICEPT is seen. There is no evidence |
& of a rebound effect after abrupt discontinuation of therapy. |
# Renal and hepatic impairment: |
– A similar dose schedule can be followed for patients with renal impairment, as clearance of donepezil hydrochloride |
& is not affected by this condition. |
– Due to possible increased exposure in mild to moderate hepatic impairment, dose escalation should be performed according |
& to individual tolerability. There are no data for patients with severe hepatic impairment. |
# ARICEPT is not recommended for use in children. |
* Do not store above 30 degrees C. |
* Manufactured by: Pfizer Egypt. Under Authority of: Pfizer Inc., USA. |
Weight | 100 kg |
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1 review for ARICEPT 5 MG 14 TAB