* Indications: | ||
& Infections caused by ceftriaxone-sensitive microorganisms, for example: | ||
– Sepsis. | ||
– Meningitis. | ||
– Abdominal infections (peritonitis, infections of the bile ducts and gastrointestinal tract). | ||
– Infections of the bones, joints, soft tissues and wounds. | ||
– Perioperative infection prophylaxis. | ||
– Infections in patients with reduced immunodefence. | ||
– Infections of the kidneys and lower urinary tract. | ||
– Infections of the respiratory passages, particularly, pneumonia, and the ear, nose and throat. | ||
– Infections of the genital organs, including gonorrhoea. | ||
– Lyme disease from the second stage. | ||
* Mode of application: | ||
– Slow (2-5 minutes) I.V. injection. | ||
& The solutions are prepared in accordance with the following: | ||
. Ceftriaxone Sandoz 250 mg: —- i.v. injection (WFI): 2 mL solvent i.m. injection (1% Lidocaine). | ||
. Ceftriaxone Sandoz 500 mg: 5 mL i.v. injection (WFI): 2 mL solvent i.m. injection (1% Lidocaine). | ||
. Ceftriaxone Sandoz 1 g: 10 mL i.v. injection (WFI): 3.5 mL solvent i.m. injection (1% Lidocaine) | ||
– Intravenous doses of 50 mg or more per Kg body weight should be administered as slow infusion over a period of at | ||
& least 30 minutes. Freshly prepared solutions remain physically and chemically stable at room temperature for 6 | ||
& hours (or 24 hours at 5 oC). As a general rule, the solutions should be used directly after preparation. | ||
* Dosage: | ||
@ Adults and children over 12 years: | ||
& Normally 1-2 g of ceftriaxone per day (every 24 hours) for severe infections of those caused by poorly susceptible | ||
& bacteria the daily dose can be increased to 4 g. | ||
@ Neonates, infants and children up to 12 years: | ||
– Neonates (up to two weeks) | ||
& Daily dose of 20 mg/kg body weight to a maximum of 50 mg/kg (depending on the severity of the infection). | ||
– Infants and children (3 weeks to 12 years) | ||
& Daily dose of 20 mg/kg body weight to a maximum of 80 mg/kg (depending on the severity of the infection). For | ||
& children weighing 50 kg or more the normal adult dose must be used. | ||
@ Elderly patients: | ||
& The recommended dosages for adults do not need to be adjusted for geriatric patients. | ||
@ Duration of treatment: | ||
& The length of treatment depends on the course of the disease. As with all antibiotic therapy, ceftriaxone should be | ||
& taken for at least 48 to 72 hours after the fever has subsided or the bacteria have been shown to have been eliminated. | ||
CEFTRIAXONE (AS SODIUM) 500 MG |
CEFTRIAXONE 500 MG I.M 1 VIAL
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