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NEXIUM 40 MG 10 VIAL
700.00 EGP
In stock
| * Composition: esomeprazole sodium 42.5mg, equivalent to esomeprazole 40mg. | ||
| * Keep the vial in the outer carton in order to protect from light. | ||
| * Indications and Usage: | ||
| – NEXIUM I.V. is indicated for the short-term treatment (up to 10 days) of GERD patients with | ||
| & a history of erosive esophagitis as an alternative to oral therapy in patients when it is not | ||
| & possible or appropriate. | ||
| – When oral therapy is possible or appropriate; I.V. therapy with NEXIUM I.V. should be discontinued | ||
| & and therapy should be continued orally. | ||
| – Children<18years: not recommended. | ||
| – Severe hepatic impairment: max 20mg/day. | ||
| * Precautions: | ||
| – Symptomatic response to therapy with NEXIUM does not preclude the presence of gastric | ||
| & malignancy. | ||
| – Atrophic gastritis has been noted occasionally in gastric corpus biopsies from patients treated | ||
| & long-term with omeprazole, of which NEXIUM is an enantiomer. | ||
| – Treatment with NEXIUM I.V. should be discontinued as soon as the patient is able to resume treatment | ||
| & with oral therapy. | ||
| – Pregnancy (Cat.B). Nursing mothers: not recommended. | ||
| * Dosage and administration: | ||
| – GERD with a history of erosive esophagitis: the recommended adult dose is either 20 or 40 mg | ||
| & esomeprazole given once daily by I.V. injection (no less than 3 minutes) or I.V. infusion (10 to 30 min). | ||
| * Preparation for use: | ||
| – I.V. injection: The powder should be reconstituted with 5mL of 0.9% Sodium Chloride Injection. | ||
| & Withdraw 5 mL of the reconstituted solution and administer as an I.V. injection over no less than 3 min. | ||
| & The reconstituted solution should be stored at room temperature up to 30 oC and administered within | ||
| & 12 hours after reconstitution. No refrigeration is required. | ||
| – I.V. infusion: A solution for I.V. infusion is prepared by first reconstituting the contents of one vial | ||
| & with 5 mL of 0.9% Sodium Chloride Injection, Lactated Ringer’s Injection, or 5% Dextrose Injection | ||
| & and further diluting the resulting solution to a final volume of 50 mL. The solution (admixture) should | ||
| & be administered as an I.V. infusion over a period of 10 to 30 minutes. The admixture should be stored | ||
| & at room temperature up to 30 oC and should be administered within the designated time period: | ||
| . 0.9% Sodium Chloride Injection: within 12 hours. | ||
| . Lactated Ringer’s Injection: within 12 hours. | ||
| . 5% Dextrose Injection: within 6 hours. | ||
| – NEXIUM I.V. should not be administered concomitantly with any other medications through the same | ||
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