* For weight loss and weight maintenace.
* Indications:
– Obesity management, including weight loss, and weight maintenance, in conjunction with dietary modification.
– Reducing weight for obese diabetic subjects.
* Precautions:
– Patients should be advised to adhere to dietary guidelines. If orlistat is taken with a meal very high in fat,
the possibility of gastrointestinal side effects increases.
– Patients should be counseled to take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition,
because orlistat is shown to reduce the absorption of some fat-soluble vitamins and beta-carotene.
The supplement should be taken at least 2 hours before or after an orlistat dose or at bedtime.
– Caution should be exercised when prescribing orlistat to patients with history of hyperoxaluria or calcium oxalate nephrolithiasis.
– Weight-loss induction by orlistat may be accompanied by improved metabolic control in diabetics, which might require
a reduction in the dose of oral hypoglycemic medication (e.g., sulfonylureas, metformin) or insulin.
– Orlistat adds to the lipid-lowering effect of pravastatin.
* Dosage and administration:
– 120 mg capsule (one capsule) three times a day with each main meal containing fat (during or up to 1 hour after the meal).
– If a meal is occasionally missed or contains no fat, the dose of Slim-Safe® can be omitted.
– Doses above 120 mg three times a day have not been shown to provide additional benefit.
* Pregnancy & Lactation:
– Pregnancy: Category B.
– It is not known if orlistat is secreted in human milk. Therefore, it should not be taken by lactating women.
* Contraindications:
– Orlistat is contraindicated in patients with chronic malabsorption syndrome or cholestasis, and in patients with known
hypersensitivity to the product.
* Store between 15-30 degrees C.
* Product of: Amoun Pharmaceutical Co. S.A.E. – Egypt.
Weight | 100 kg |
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