ARTH FREE ( LEFLUNOMIDE ) 20 MG 30 TAB

* Indications:
  For the treatment of Rheumatoid Arthritis.
* Dosage:
  – It is recommended to initiate therapy with a loading dose of one Arthfree 100 mg
  tablets once per day for 3 days followed by a maintenance daily dose of one tablet of
  Arthfree 20 mg tablets once daily.
  – If dosing at 20 mg/day is not well tolerated clinically, the dose may be decreased to
  10 mg daily.
* Contra-indications:
  – Hypersensitivity to leflunomide.
  – Pregnancy and lactation.
  – Not recommended for patients less than 18 years.
* Precautions:
  – Therapy with leflunomide might be associated in some cases with mild elevation in
  liver enzymes (twofold) and this elevation returns to normal with continuation of
  therapy. However if the elevation is too high or if levels of liver enzymes are not
  normalized along therapy, especially in case of concomitant administration of other
  drugs that affect the liver, dosage adjustment or discontinuation of therapy is
  advisable. In most of the cases, it is preferable to have a baseline measure for the
  liver enzymes levels.
  – Caution should be taken when leflunomide is administered to patients with renal
  insufficiency. The use of leflunomide in patients with hepatic insufficiency is not
  recommended.
* Store in a dry place, at a temperature not exceeding 30 degrees C.
* Manufactured by: EVA PHARMA for Pharmaceuticals & Medical Appliances S.A.E – Egypt.